Molecular Biomarkers for Gestational Diabetes Mellitus

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Gestational diabetes mellitus

Introduction: Gestational diabetes mellitus (GDM) is defined as any degree of glucose intolerance with onset or first recognition during pregnancy. The prevalence range from 1 to 14% of all pregnancies, depending on the population studied and the diagnostic tests employed. Risk assessment for GDM should be undertaken at the prenatal visit. Women with clinical characteristics of GDM should und...

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Clinical evidence has revealed the association between complications Diabetes Mellitus (DM) and serum glycemic control. Thus, evaluation of the glycemic control status is crucial in the management of DM. Hemoglobin A1c (HbA1c) is the most common method for monitoring serum glycemic control. However, several confounding factors including red blood cell lifespan and hemoglobinopathies can affect ...

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Application of adjusted-receiver operating characteristic curve analysis in combination of biomarkers for early detection of gestational diabetes mellitus

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Screening for gestational diabetes mellitus.

OBJECTIVE The purpose of this document is to briefly review the existing data regarding the effect of a diagnosis of gestational diabetes mellitus (GDM), the different screening and diagnostic practices for GDM, and, finally, outline the recommended options for GDM screening in Canada. OPTIONS Consideration has been given to the existing screening practices for GDM including universal screeni...

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Gestational Diabetes Mellitus

DIAGNOSTIC CRITERIA The oral glucose tolerance test (OGTT) most commonly used to diagnose GDM in the United States is the 3-hour, 100-g OGTT. According to diagnostic criteria recommended by the American Diabetes Association (ADA), GDM is diagnosed if two or more plasma glucose levels meet or exceed the following thresholds: fasting glucose concentration of 95 mg/dl, 1-hour glucose concentration...

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ژورنال

عنوان ژورنال: International Journal of Molecular Sciences

سال: 2018

ISSN: 1422-0067

DOI: 10.3390/ijms19102926